How Not to Age

The Latest Clinical Trial of Turmeric Curcumin for Alzheimer’s Disease Treatment

Can turmeric really sharpen memory within hours?

A large blue glass container on its side with spilled white taurine powder with a yellow measuring scoop in the center of the powder pile in front of a mint green background

Like Beet Juice, Taurine Supplementation May Only Be Safe in the Context of a Plant-Based Diet

The adverse effects of taurine on our microbiome and hydrogen sulfide production may be ameliorated by diets high in fiber and low in saturated fats.

Dark wooden chopsticks holding up a dried seaweed nori sheet in front of a light

Where to Find Taurine and the Best Source

I compare the cost, convenience, and safety of various plant, animal, and supplement sources of taurine.

Closeup view of white tablets of taurine supplements on a white background

The Best Daily Dose of Taurine

Even researchers from the pro-taurine anti-aging study recommend against experimenting with taurine, but if you want to give it a try, what daily dose might be best?

Wooden tray filled with taurine supplement capsules

Caveats and Side Effects of Taurine Supplements

What are the downsides of taurine supplementation?

Close up view of a scoop of taurine powder

Randomized Controlled Trials of Taurine Supplementation in Humans

Cautionary tales from carnitine and arginine complicate the taurine supplementation question.

Close portrait of a dog with tan and white colored fur raising their paw

Taurine Supplementation Increases Lifespan and Healthspan in Animals

The level of taurine in our bodies declines with age, dropping by nearly 80 percent. Would consuming extra improve lifespan or healthspan?

Close up view of metal cans of energy drinks

What Is Taurine in Energy Drinks? Does It Benefit Cognitive or Athletic Performance?

We have at least five pathways to make taurine in our body from scratch, but does taking more offer a benefit?

The Benefits and Side Effects of Red and Green Rooibos Teas

Is green rooibos (analogous to green tea) healthier than red rooibos, the commercially more common oxidized form that’s akin to black tea?

Drawing of a double helix on a blue background

The Third Way to Boost NAD+

How can we conserve NAD+ by preventing overactivation of the enzymes PARP-1 and CD38, which guzzle NAD+?

Which NAD+ Booster Is Best?

You can naturally get your body to make more NAD+ by boosting the NAD+ synthesizing enzyme NAMPT.

White tablets from a bottle onto blue surface

Risks of NAD+ Boosting Supplements

Particular caution should be used for NAD+-boosting supplements by those with cancer, a personal or strong family history of cancer and perhaps also by those with inflammatory disorders and certain active infections.

Lesser-Known NAD+ Boosting Supplements—Tryptophan, NADH, NMNH, and NRH

What are the pros, cons, and efficacy of dihydronicotinamide riboside (reduced NR), perhaps the most potent NAD+ precursor, as well as reduced NMN, taking NAD+ directly, or making it from scratch from tryptophan?

Risks and Benefits of Nicotinamide Mononucleotide (NMN), a NAD+ Booster

NR may just be a waste of money, safe but ineffective. NMN seems similarly useless in humans, but it may not even be safe.

Risks and Benefits of Nicotinamide Riboside (NR), a NAD+ Booster

The suppression of NAD+ synthesis by NR in humans may explain the disparate rodent results.

Person taking a supplement capsule with a cup of water

Risks and Benefits of Nicotinamide (NAM), a NAD+ Booster

The metabolism of NAM may deplete our methylation capacity, interfering with the normal metabolism of hormones and neurotransmitters, and produce a neurotoxic compound in the process.

Risks and Benefits of Nicotinic Acid (NA), a NAD+ Booster

Given niacin’s decades of use as a cholesterol drug, we have a good idea of its safety profile.

Can NAD+ Boosters Increase Lifespan and Healthspan?

The effects of NAD+ boosters on aged rodents have been described in the medical literature as “profound,” “dramatic,” and “remarkable,” but do they help people?

Do NAD+ Levels Decline with Age?

What is NAD+ and what role does it play in the aging process?

digital illustration of NAD+ in blue and white

The Best Way to Boost NAD+: Supplements vs. Diet (webinar recording)

The pros and cons of all the NAD+ supplements and what are the ways to boost NAD+ naturally with diet and lifestyle?

Digital illustration of sperm cells chasing an egg cell

The Trade-Off Between Fertility and Longevity, and Causes of Precocious Puberty

A century ago, the age of first menstruation averaged as late as nearly 17. Why is sexual maturity coming so much earlier now?

Close up shot of someone squeezing the brake on their bike handles

The Enzyme mTOR as an Engine of Aging

Inhibiting mTOR, the “master determinant of lifespan,” is considered the best validated aging regulator.

Woman undergoing laser therapy at the hairline

Do Low-Level Laser Therapy Devices Work for Hair Loss?

Laser therapy is marketed as a promising alternative to drugs and scalpels for treating hair loss, but what does the research say?

Cognitive Stimulation, Music Therapy, and Cryostimulation to Improve Cognitive Function

What were the findings of an analysis of common, non-drug, non-supplement, non-lifestyle approaches to dementia prevention and treatment?

Do Collagen Supplements Work for Skin Aging?

I assumed that collagen proteins would get completely broken down in the digestive tract, but I was wrong.

Ginkgo and Nicotinamide for Glaucoma Treatment

How do two common supplements stack up against glaucoma, the leading cause of irreversible vision loss in the world?

Dr. Greger and the presentation title on a blue background

How Not To Age – Live Presentation

In this live lecture, Dr. Greger offers a sneak peek into his latest book, How Not to Age, a New York Times Best Seller.

Senior couple walking on the beach holding hands and barefoot at sunrise

Is It Possible to Reverse Aging and Live Forever?

Some animals, like the immortal jellyfish, can effectively live forever, so why can’t we?

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Book Trailer for How Not to Age

Learn about my newest book, How Not to Age, a New York Times Best Seller.

All Videos for How Not To Age