NAD+

Closeup view of white tablets of taurine supplements on a white background

The Best Daily Dose of Taurine

Even researchers from the pro-taurine anti-aging study recommend against experimenting with taurine, but if you want to give it a try, what daily dose might be best?

Drawing of a double helix on a blue background

The Third Way to Boost NAD+

How can we conserve NAD+ by preventing overactivation of the enzymes PARP-1 and CD38, which guzzle NAD+?

Which NAD+ Booster Is Best?

You can naturally get your body to make more NAD+ by boosting the NAD+ synthesizing enzyme NAMPT.

White tablets from a bottle onto blue surface

Risks of NAD+ Boosting Supplements

Particular caution should be used for NAD+-boosting supplements by those with cancer, a personal or strong family history of cancer and perhaps also by those with inflammatory disorders and certain active infections.

Lesser-Known NAD+ Boosting Supplements—Tryptophan, NADH, NMNH, and NRH

What are the pros, cons, and efficacy of dihydronicotinamide riboside (reduced NR), perhaps the most potent NAD+ precursor, as well as reduced NMN, taking NAD+ directly, or making it from scratch from tryptophan?

Risks and Benefits of Nicotinamide Mononucleotide (NMN), a NAD+ Booster

NR may just be a waste of money, safe but ineffective. NMN seems similarly useless in humans, but it may not even be safe.

Risks and Benefits of Nicotinamide Riboside (NR), a NAD+ Booster

The suppression of NAD+ synthesis by NR in humans may explain the disparate rodent results.

Person taking a supplement capsule with a cup of water

Risks and Benefits of Nicotinamide (NAM), a NAD+ Booster

The metabolism of NAM may deplete our methylation capacity, interfering with the normal metabolism of hormones and neurotransmitters, and produce a neurotoxic compound in the process.

Risks and Benefits of Nicotinic Acid (NA), a NAD+ Booster

Given niacin’s decades of use as a cholesterol drug, we have a good idea of its safety profile.

Can NAD+ Boosters Increase Lifespan and Healthspan?

The effects of NAD+ boosters on aged rodents have been described in the medical literature as “profound,” “dramatic,” and “remarkable,” but do they help people?